EVALUATION OF THE INTAKE OF NITRATE, NITRITE, NITROSODIETHYLAMINE AND NITROSODIMETHYLAMINE BY FOOD CONSUMPTION
Keywords:nitrates, nitrites, nitrosamines, food, diet
The aim of the present study was the evaluation of nitrate, nitrite, nitrosodiethylamine (NDEA) and nitrosodimethylamine (NDMA) intake by food consumption. We determined concentrations of nitrates, nitrites in 102 food samples (40 meat products, 15 fermented cheese, 25 vegetables, 22 fruits) and the concentration NDEA, NDMA in 40 meat products. Nitrates and nitrites were determined using Peter-Griess method; nitrosamines were quantified by HPLC with UV detection. We designed vegetalian, vegetarian and conventional diets of about 2500 kcal/day. Based of the values found, we calculated the intake of nitrates, nitrites and nitrosamines. The obtained values fits to WHO’s recommendations, except for vegetalian and conventional diet, in which the nitrate content was 3,46 respectively 1,64 times higher than the acceptable daily intake (157 mg NO3-/day).
BRYAN N.S., ALEXANDER D.D., COUGHLIN J.R., MILKOWSKI A.L., BOFFETA P. (2012) Ingested nitrate and nitrite and stomach cancer risk : An updated rewiew. Food and Chemical Toxicology, 50:3646-3665.
FYTIANOS K., ZAROGIANNIS P. (1999) Nitrate and nitrite accumulation in fresh vegetables from Greece. Bulletin on Environment Contamination and Toxicology, 62:187-192.
EFSA (2008) Nitrate in vegetables. Scientific Opinion of the Panel on Contaminants in the Food Chain, EFSA Journal, 689:1-79.
HORWITZ W. (2000) Official Methods of Analysis of AOAC International, 17th Edition, vol.II, Gaithersburg, Maryland.
IAMMARINO M., DI TARANTO A., CRISTINO M. (2013) Endogenous levels of nitrites and nitrates in wide consumtion foodstuffs: Results of five years of official controls and monitoring. Food Chemistry, 140:763-771.
MITACEK E.J., BRUNNEMANN K.D., SUTTAJIT M., MARTIN N., LIMSILA T., OHSHIMA H., CAPLAN N. (1999) Exposure to N-Nitroso Compounds in a Population of High Liver Cancer Regions in Thailand: Volatile Nitrosamine (VNA) Levels in Thai Food. Food and Chemical Toxicology, 37:297-305.
TAMME T., RENIK M., ROASTO M. (2010) Nitrates and Nitrites in Vegetables: Occurrence and Health Risks. In: Watson RR, Preedy VR. Bioactive foods in promoting health. Fruits and vegetables. Amsterdam, Boston: Academic Press, TAMME T., REINIK M., ROASTO M., JUHKAM E., TENNO T., KILS A. (2006) Nitrates and nitrites in vegetables and vegetables-besed products and their intakes by the Estonian population. Food Additives and Contaminants, 23:355-361.
SINDELAR J.J, MILKOWSKI A.L. (2012) Human safety controversies surrounding nitrate and nitrite in the diet. Nitric Oxide, 26:259-266.
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Copyright (c) 2014 Liliana Avasilcai, Marieta Nichifor, Geanina Bireescu, Rodica Cuciureanu
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